Description

Anp 1-28, Human is a synthetic peptide fragment corresponding to the N-terminal region of human Atrial Natriuretic Peptide (ANP). This high-purity biochemical is a critical research tool for studying cardiovascular physiology, renal function, and related endocrine pathways. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and academic research sectors who require reliable, well-characterized peptides for assay development, receptor binding studies, and as a reference standard.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of natriuresis, diuresis, and vasodilation mechanisms.
• Assay Development: Critical for the development and validation of immunoassays (ELISA, RIA) to detect and quantify ANP levels in biological samples.
• Receptor Binding Studies: Employed in competitive binding assays to study the affinity and kinetics of the natriuretic peptide receptor A (NPR-A).
• Pharmaceutical R&D: Serves as a key intermediate or reference compound in the discovery and development of cardiovascular therapeutics.
• Quality Control: Used as a system suitability standard in analytical laboratories to ensure the performance of chromatographic methods for peptide analysis.

Basic Information

Product Name	Anp 1-28, Human
CAS No.	89213-87-6
Molecular Formula	C128H205N41O39S2
Molecular Weight	3080.4 g/mol
Synonyms	Atrial Natriuretic Peptide (1-28), human; ANP (1-28); Atriopeptin 28; Cardionatrin I; Auriculin A; α-ANP; hANP; Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge: Cys7-Cys23)
EINECS	Contact for details

Quality Control

Every batch of Anp 1-28, Human is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and a detailed Certificate of Analysis (COA) with each shipment, which includes data for purity (HPLC), peptide content, amino acid analysis, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or aqueous acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.