Description

5-Pyrimidinethiol, 4-Amino-2-Methyl- (7Ci) is a specialized heterocyclic building block featuring a pyrimidine core functionalized with thiol and amino groups. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides where the pyrimidine scaffold is a common bioactive motif.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science: Potential monomer or modifier in the development of advanced polymers and functional organic materials.
• Bioconjugation Chemistry: The thiol group enables its use in site-specific bioconjugation strategies for labeling proteins or other biomolecules.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	5-Pyrimidinethiol, 4-Amino-2-Methyl- (7Ci)
CAS No.	89180-11-0
Molecular Formula	C5H7N3S
Molecular Weight	141.19 g/mol
Synonyms	4-Amino-2-methylpyrimidine-5-thiol; 2-Methyl-4-aminopyrimidine-5-thiol; 4-Amino-2-methyl-5-pyrimidinethiol; 4-Amino-2-methyl-5-mercaptopyrimidine; 5-Mercapto-4-amino-2-methylpyrimidine; 2-Methyl-4-amino-5-mercaptopyrimidine; 4-Amino-2-methylpyrimidine-5-thione (tautomer)
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinethiol, 4-Amino-2-Methyl- (7Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (by HPLC), related substances, and residual solvents. Our quality systems support development from research quantities to commercial scale, ensuring reliable supply for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.