Description

Cholera Toxin, B Subunit (50-64) is a synthetic peptide fragment corresponding to amino acid residues 50-64 of the B subunit of cholera toxin. This well-defined peptide is a critical research tool for studying the structure, function, and immunology of cholera toxin, particularly its receptor-binding domain. It is primarily utilized by researchers and developers in the fields of vaccinology, immunology, and infectious disease diagnostics. The compound is supplied as a high-purity material to ensure reliable and reproducible experimental results.

Application

• Biomedical Research: Used as a key antigen in immunological studies to investigate antibody responses and toxin neutralization mechanisms.
• Vaccine Development: Serves as a reference standard or a component in the research and development of subunit vaccines against cholera.
• Diagnostic Assays: Employed in the development and calibration of ELISA and other immunoassays for detecting cholera toxin or specific antibodies.
• Receptor Binding Studies: Essential for probing the interaction between the cholera toxin B subunit and its cellular receptor, GM1 ganglioside.
• Structural Biology: Used in X-ray crystallography and NMR studies to elucidate the three-dimensional structure and binding epitopes of the toxin.
• Quality Control: Acts as a reference standard for the quality assessment of related biological products and reagents.

Basic Information

Product Name	Cholera Toxin, B Subunit (50-64)
CAS No.	89157-28-8
Molecular Formula	C73H118N22O24S
Molecular Weight	1687.9 g/mol
Synonyms	CTB (50-64); Cholera Toxin B Subunit Peptide (50-64); Cholera Enterotoxin B Subunit Fragment 50-64; CTXB (50-64); H-Thr-Asn-Leu-Thr-Ile-Thr-Ala-Gly-Tyr-Asn-Glu-Ala-Leu-Ile-OH; TNLTIAGYNEALI; TNLTIAGYNEALI-OH
EINECS	Contact for details

Quality Control

Every batch of our Cholera Toxin, B Subunit (50-64) is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, HPLC profile, mass spectrometry data, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values
Molecular Weight (MS)	1687.9 ± 2.0 Da
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 70%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.