Description

4-Iodo-6-Methylsulfanyl-Pyrimidine is a halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the construction of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on nucleoside analogs, kinase inhibitors, and other active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside analogs and antiviral agents.
• Agrochemical Research: Building block for developing new herbicides and fungicides with specific modes of action.
• Material Science: Used in the creation of functionalized ligands for catalysis and advanced polymeric materials.
• Chemical Biology: Serves as a probe or labeling agent in biochemical studies due to its reactive iodine moiety.
• Cross-Coupling Reactions: Essential substrate in palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings for carbon-carbon bond formation.
• Library Synthesis: Employed in high-throughput and combinatorial chemistry for generating diverse compound libraries for screening.

Basic Information

Product Name	4-Iodo-6-Methylsulfanyl-Pyrimidine
CAS No.	89125-96-2
Molecular Formula	C5H5IN2S
Molecular Weight	251.08 g/mol
Synonyms	4-Iodo-6-(methylthio)pyrimidine; 6-Methylsulfanyl-4-iodopyrimidine; 4-Iodo-6-methylmercaptopyrimidine; 4-Iodo-6-(methylsulfanyl)pyrimidine; Pyrimidine, 4-iodo-6-(methylthio)-; 89125-96-2; 4-Iodo-6-methylsulfanylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Iodo-6-Methylsulfanyl-Pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued lighting or in amber glass containers when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.