Description

[2-[[4-(Aminosulphonyl)Phenyl]Amino]-1,4-Dihydro-4-Oxo-5-Pyrimidinyl]Carbamoyl Chloride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a key building block for constructing complex heterocyclic molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel sulfonamide-based therapeutics and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel sulfonamide-containing drug candidates, particularly for therapeutic areas requiring pyrimidine scaffolds.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its bioactive sulfonamide and heterocyclic structure.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex, high-value specialty chemicals and dyes.
• Biochemical Probe Development: Employed in research to create enzyme inhibitors or molecular probes targeting biological pathways.
• Material Science: Potential intermediate for synthesizing functional polymers or advanced materials with specific chemical properties.

Basic Information

Product Name	[2-[[4-(Aminosulphonyl)Phenyl]Amino]-1,4-Dihydro-4-Oxo-5-Pyrimidinyl]Carbamoyl Chloride
CAS No.	89074-09-9
Molecular Formula	C11H10ClN5O4S
Molecular Weight	343.74 g/mol
Synonyms	5-[(Chlorocarbonyl)amino]-2-[[(4-sulfamoylphenyl)amino]-1,4-dihydro-4-oxopyrimidine; 5-Isocyanatocarbonyl-2-[(4-sulfamoylanilino)]-4(1H)-pyrimidinone; 2-[(4-Sulfamoylanilino)-4-oxo-1,4-dihydro-5-pyrimidinyl]carbamoyl chloride; 5-Pyrimidinecarboxamide, 2-[[4-(aminosulfonyl)phenyl]amino]-1,4-dihydro-4-oxo-, chloride; Sulfapyrimidine carbamoyl chloride derivative; N-(4-Sulfamoylphenyl)-4-oxo-5-carbamoylchlorido-1,4-dihydropyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our [2-[[4-(Aminosulphonyl)Phenyl]Amino]-1,4-Dihydro-4-Oxo-5-Pyrimidinyl]Carbamoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, strong oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.