Description

n-Methylorphenadrine Methosulfate is a quaternary ammonium salt derivative of orphenadrine, valued for its potent anticholinergic and muscle relaxant properties. This compound is a critical active pharmaceutical ingredient (API) and a key intermediate in the synthesis of specialized therapeutic agents. It is primarily required by pharmaceutical manufacturers and advanced research institutions developing treatments for conditions involving muscle spasticity and central nervous system disorders.

Application

• Primary Active Pharmaceutical Ingredient (API) in prescription muscle relaxant formulations.
• Key chemical intermediate in the synthesis of advanced anticholinergic drugs.
• Reference standard for quality control and analytical method development in pharmaceutical laboratories.
• Research chemical in pharmacological studies targeting muscarinic acetylcholine receptors.
• Starting material for the development of novel neuropharmaceuticals.

Basic Information

Product Name	n-Methylorphenadrine Methosulfate
CAS No.	89066-67-1
Molecular Formula	C19H27NO4S
Molecular Weight	365.49 g/mol
Synonyms	N-Methylorphenadrine Methanesulfonate; Orphenadrine N-Methyl Methosulfate; N-Methyl Orphenadrine Methyl Sulfate; 2-[(2-Benzhydryloxyethyl)-methylamino]ethanol methanesulfonate; N-Methylorphenadrine Mesylate; N-Methyl orphenadrine methanesulphonate; N-Methyl orphenadrine methylsulfate salt
EINECS	Contact for details

Quality Control

Our n-Methylorphenadrine Methosulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with every shipment to guarantee supply chain integrity and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.