Description

Sauvagine(17-40) is a bioactive peptide fragment derived from the full-length sauvagine peptide. This compound is a critical research tool for studying the corticotropin-releasing factor (CRF) receptor system and related stress response pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on neuroendocrinology, stress-related disorders, and drug discovery.

Application

• Neuroscientific Research: Used as a selective ligand for investigating the binding and functional activity of CRF receptors in the central nervous system.
• Pharmacological Studies: Serves as a reference standard and tool compound in assays for screening and characterizing novel CRF receptor antagonists or agonists.
• Endocrine System Research: Applied in studies exploring the hypothalamic-pituitary-adrenal (HPA) axis and its role in stress, anxiety, and metabolic regulation.
• Biochemical Assay Development: Employed in the development and validation of competitive binding assays (e.g., radioimmunoassays, fluorescence polarization).
• Cell Signaling Pathways: Used to stimulate intracellular signaling cascades (e.g., cAMP production) in cell-based models to study receptor downstream effects.
• Academic & Institutional Labs: A key reagent for basic research in physiology and peptide hormone action.

Basic Information

Product Name	Sauvagine(17-40)
CAS No.	88831-26-9
Molecular Formula	C₁₁₀H₁₇₀N₃₂O₃₃
Molecular Weight	~2475.8 g/mol
Synonyms	Sauvagine (17-40), human; Sauvagine fragment 17-40; CRF (Corticotropin-Releasing Factor) related peptide; Tyr-Gly-Pro-Pro-Ile-Ser-Ile-Asp-Leu-Ser-Phe-Gln-His-Lys-Leu-Leu-Glu-Glu-Val-Glu-Ile-Ala-NH2; H-Tyr-Gly-Pro-Pro-Ile-Ser-Ile-Asp-Leu-Ser-Phe-Gln-His-Lys-Leu-Leu-Glu-Glu-Val-Glu-Ile-Ala-NH2; [Tyr⁰]Sauvagine(17-40); Urocortin-related peptide.
EINECS	Contact for details

Quality Control

Our Sauvagine(17-40) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, peptide content, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.