Description

3-(Difluoromethoxy)Phenol is a versatile fluorinated phenolic compound, serving as a critical building block in advanced organic synthesis. Its unique difluoromethoxy-substituted aromatic structure provides valuable chemical and physical properties for developing high-performance materials and active ingredients. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine for enhanced bioactivity and stability.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, where the difluoromethoxy group can improve lipophilicity and biological activity.
• Liquid Crystal Materials: Used in the development of fluorinated components for liquid crystal displays (LCDs) to modify dielectric anisotropy and improve performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance thermal stability, chemical resistance, and surface properties.
• Organic Synthesis Research: A valuable reagent for academic and industrial R&D in exploring new fluorination methodologies and creating complex molecular architectures.
• Dye & Pigment Intermediate: Serves in the production of specialized dyes and pigments requiring fluorine substitution for color fastness and durability.

Basic Information

Product Name	3-(Difluoromethoxy)Phenol
CAS No.	88798-13-4
Molecular Formula	C7H6F2O2
Molecular Weight	160.12 g/mol
Synonyms	3-(Difluoromethoxy)phenol; Phenol, 3-(difluoromethoxy)-; m-(Difluoromethoxy)phenol; 3-Hydroxyphenyl difluoromethyl ether; 1-Hydroxy-3-(difluoromethoxy)benzene; DFMP
EINECS	Contact for details

Quality Control

Our 3-(Difluoromethoxy)Phenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.