Description

3-(4-Amino-1H-Pyrrolo(2,3-D)Pyrimidin-1-Yl)-5-(Hydroxymethyl)-1,2-Cycl Opentanediol is a high-purity nucleoside analog intermediate of significant importance in modern pharmaceutical synthesis. This compound matters for its role as a critical building block in the development of novel antiviral and anticancer therapeutics, where precise molecular structure is paramount. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of nucleoside-based active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex nucleoside analogs and related prodrugs.
• Antiviral Drug Research: Serves as a core scaffold for developing novel antiviral agents targeting viral polymerases.
• Oncology Therapeutics: Used in the research and development of anticancer compounds that interfere with DNA/RNA synthesis.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and mechanism-of-action investigations.
• Process Chemistry & Scale-Up: Utilized in route development and optimization for the commercial manufacturing of target APIs.
• Custom Synthesis: A starting material for the custom synthesis of labeled compounds (e.g., deuterated, C13) for metabolic and pharmacokinetic studies.

Basic Information

Product Name	3-(4-Amino-1H-Pyrrolo(2,3-D)Pyrimidin-1-Yl)-5-(Hydroxymethyl)-1,2-Cycl Opentanediol
CAS No.	88767-13-9
Molecular Formula	C12H15N5O4
Molecular Weight	293.28 g/mol
Synonyms	1-(5-(Hydroxymethyl)-1,2-cyclopentanediol-3-yl)-4-aminopyrrolo[2,3-d]pyrimidine; 4-Amino-1-((1S,2R,3S)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)-1H-pyrrolo[2,3-d]pyrimidine; Carbocyclic Nucleoside Analog Intermediate; Cyclopentyl Pyrrolopyrimidine Derivative; c-Nucleoside Intermediate; 88767-13-9; 4-Amino-7-((1S,2R,3S)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 3-(4-Amino-1H-Pyrrolo(2,3-D)Pyrimidin-1-Yl)-5-(Hydroxymethyl)-1,2-Cycl Opentanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all critical quality attributes are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.