Description

H-Phe-Leu-Oet Hcl is a protected dipeptide derivative, specifically the ethyl ester hydrochloride salt of the phenylalanine-leucine sequence. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled construction of complex peptides and proteins. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing therapeutic peptides, biochemical tools, and novel bioactive compounds.

Application

• Peptide Synthesis Intermediate: A key protected fragment for the stepwise assembly of longer peptide chains in both research and GMP manufacturing.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs targeting metabolic disorders, oncology, and cardiovascular diseases.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and for probing protein-protein interactions.
• Cosmetic Peptide Development: A potential raw material in the synthesis of bioactive peptides for advanced skincare formulations.
• Academic Research: Employed in university and institutional labs for studying peptide chemistry, structure-activity relationships (SAR), and molecular biology.
• Fine Chemical Production: An intermediate in the custom synthesis of specialty peptides and chiral compounds for various industrial applications.

Basic Information

Product Name	H-Phe-Leu-Oet Hcl
CAS No.	88767-10-6
Molecular Formula	C20H29ClN2O4
Molecular Weight	396.91 g/mol
Synonyms	L-Phenylalanyl-L-leucine ethyl ester hydrochloride; Phe-Leu-OEt·HCl; Ethyl L-phenylalanyl-L-leucinate hydrochloride; N-(Benzyloxycarbonyl)-L-phenylalanyl-L-leucine ethyl ester hydrochloride (related protected form); H-Phe-Leu-OEt hydrochloride; F-L-OEt HCl; Z-Phe-Leu-OEt HCl (common precursor); Peptide fragment 88767-10-6
EINECS	Contact for details

Quality Control

Our H-Phe-Leu-Oet Hcl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and NMR/IR for structural confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.