Description

o-(2-Acetamido-2-Deoxy-α-Galactopyranosyl)-(1-3)-n-Acetylserine Methyl Ester is a specialized glycosylated amino acid derivative of significant interest in advanced biochemical research and synthesis. This compound serves as a crucial building block and reference standard for studying glycosylation patterns, protein-carbohydrate interactions, and glycopeptide synthesis. It is primarily utilized by research institutions and pharmaceutical development teams focused on glycobiology, glycoengineering, and the development of novel therapeutic agents, including vaccines and targeted biologics.

Application

• Glycopeptide & Glycoprotein Research: A key intermediate for the chemical and enzymatic synthesis of complex glycopeptides to study structure-function relationships.
• Bioconjugation & Probe Development: Used in the development of fluorescent or affinity-labeled probes for detecting and analyzing carbohydrate-binding proteins (lectins).
• Enzymatic Substrate: Acts as a specific substrate for glycosyltransferases, glycosidases, and other enzymes involved in carbohydrate metabolism for kinetic and mechanistic studies.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control in the development of glycoprotein-based therapeutics.
• Synthetic Biology & Glycoengineering: Employed in pathways designed to produce engineered glycoproteins with tailored glycosylation profiles for improved efficacy and stability.
• Diagnostic Reagent Development: Utilized in the formulation of diagnostic assays and kits targeting specific glycan biomarkers associated with diseases.

Basic Information

Product Name	o-(2-Acetamido-2-Deoxy-α-Galactopyranosyl)-(1-3)-n-Acetylserine Methyl Ester
CAS No.	88732-39-2
Molecular Formula	C16H26N2O10
Molecular Weight	406.39 g/mol
Synonyms	N-Acetyl-α-D-galactosaminyl-L-serine methyl ester; α-D-GalNAc-(1→3)-L-Ser-OMe, N-Acetylated; O-(2-Acetamido-2-deoxy-α-D-galactopyranosyl)-(1→3)-N-acetyl-L-serine methyl ester; Glycopeptide building block GalNAc-α-Ser-OMe; Tn antigen derivative methyl ester; N-Acetyl-α-D-galactosaminylserine methyl ester; Ac-α-GalNAc-Ser-OMe
EINECS	Contact for details

Quality Control

Our o-(2-Acetamido-2-Deoxy-α-Galactopyranosyl)-(1-3)-n-Acetylserine Methyl Ester is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and MS for identity verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container should be sealed under an inert atmosphere after opening and allowed to equilibrate to room temperature before use to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.