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Argipressin, β-Mercapto-(Beta,Beta)Cyclopentamethylenepropionic Acid(1)-Ile(2)-Thr(4)- CAS NO 88686-54-8


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CAS No.:88686-54-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Argipressin, β-Mercapto-(Beta,Beta)Cyclopentamethylenepropionic Acid(1)-Ile(2)-Thr(4)- is a synthetic, cyclic peptide analog of vasopressin, engineered for enhanced receptor selectivity and metabolic stability. This high-purity compound is critical for advanced pharmaceutical research and development, particularly in the study of cardiovascular and renal systems. It serves as a key reference standard and active pharmaceutical ingredient (API) for researchers and manufacturers in the global life sciences sector.

Application

  • Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in API and finished drug product manufacturing.
  • Biomedical Research: A vital tool for in vitro and in vivo studies of vasopressin receptor (V1a, V2) pharmacology, signal transduction, and physiological effects.
  • Drug Discovery & Development: Serves as a lead compound or intermediate for developing novel therapeutics targeting conditions like diabetes insipidus, septic shock, and bleeding disorders.
  • Peptide Chemistry Studies: Utilized in academic and industrial research to study structure-activity relationships (SAR) of modified peptide hormones.
  • Diagnostic Agent Development: Potential use in the formulation of diagnostic kits for assessing renal function and water balance disorders.

Basic Information

Product Name Argipressin, β-Mercapto-(Beta,Beta)Cyclopentamethylenepropionic Acid(1)-Ile(2)-Thr(4)-
CAS No. 88686-54-8
Molecular Formula C46H65N13O12S2
Molecular Weight 1040.2 g/mol
Synonyms d(CH2)5[Tyr(Me)^2,Thr^4,Tyr-NH2^9]OVT; [1-β-Mercapto-β,β-cyclopentamethylenepropionic acid, 2-O-methyltyrosine, 4-threonine, 9-tyrosinamide]vasopressin; Desmopressin analog; Vasopressin V1a receptor antagonist; β-Mercapto-β,β-cyclopentamethylenepropionyl1-Tyr(Me)2-Ile4-Thr9-Tyr-NH29-vasopressin; Cyclo(1-6)Penicillamine Vasopressin Analog; Contact for additional synonyms.
EINECS Contact for details

Quality Control

Our Argipressin, β-Mercapto-(Beta,Beta)Cyclopentamethylenepropionic Acid(1)-Ile(2)-Thr(4)- is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms
Purity (HPLC) ≥ 95.0%
Single Impurity (HPLC) ≤ 2.0%
Water Content (KF) ≤ 8.0%
Peptide Content ≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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