Description

2-(1,1,2,2-Tetrafluoroethoxy)Phenol is a specialized fluorinated phenolic compound, serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring a tetrafluoroethoxy substituent, provides valuable properties such as enhanced lipophilicity and metabolic stability for target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing next-generation active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated motifs for improved bioavailability and target binding.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorinated group can enhance activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic displays and optical devices.
• Polymer Modification: Acts as a functional monomer or additive to introduce fluorine into polymer chains, altering surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Building Block: A versatile reagent for introducing the 2-(1,1,2,2-tetrafluoroethoxy)phenyl group into more complex molecular architectures in medicinal and material chemistry.

Basic Information

Product Name	2-(1,1,2,2-Tetrafluoroethoxy)Phenol
CAS No.	88553-88-2
Molecular Formula	C8H6F4O2
Molecular Weight	210.13 g/mol
Synonyms	2-(1,1,2,2-Tetrafluoroethoxy)phenol; 2-(Perfluoroethoxy)phenol; Phenol, 2-(1,1,2,2-tetrafluoroethoxy)-; 1-Hydroxy-2-(1,1,2,2-tetrafluoroethoxy)benzene; 2-Hydroxyphenyl 1,1,2,2-tetrafluoroethyl ether; Tetrafluoroethoxyphenol
EINECS	Contact for details

Quality Control

Our 2-(1,1,2,2-Tetrafluoroethoxy)Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.