Description

Nalpha-Acetyl-L-Arginine Amide Hydrochloride is a chemically modified derivative of the essential amino acid L-arginine, featuring acetylation at the N-alpha position and amidation, supplied as a hydrochloride salt. This modification enhances its stability and bioavailability, making it a valuable building block for advanced biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications ranging from peptide synthesis to the study of cellular signaling pathways.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon in the research and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or standard in enzymatic studies, particularly those involving arginine metabolism and nitric oxide synthase pathways.
• Peptide Synthesis: An important protected arginine derivative for solid-phase and solution-phase peptide synthesis, facilitating the construction of complex peptide sequences.
• Cell Culture & Media Supplements: May be employed as a specialized component in cell culture media for studying specific metabolic processes.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Nalpha-Acetyl-L-Arginine Amide Hydrochloride
CAS No.	88530-28-3
Molecular Formula	C8H18N6O2 • HCl
Molecular Weight	266.73 g/mol (Free base: 230.27)
Synonyms	N-α-Acetyl-L-argininamide hydrochloride; Ac-Arg-NH2 • HCl; N-Acetyl-L-arginine amide hydrochloride; L-Arginine, N-acetyl-, amide, hydrochloride; Nalpha-Acetylargininamide hydrochloride; N-Acetylargininamide monohydrochloride; (S)-2-Acetamido-5-guanidino-N-(aminomethyl)pentanamide hydrochloride
EINECS	Contact for details

Quality Control

Our Nalpha-Acetyl-L-Arginine Amide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.