Description

Ddz-Gln-Oh is a specialized amino acid derivative, specifically an N-protected glutamine, widely used in peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks to construct complex peptides and proteins with precision. It is an essential reagent for pharmaceutical R&D, biotechnology, and academic laboratories focused on developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the sequential assembly of peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for constructing specific peptide fragments.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) for peptide-based drugs.
• Bioconjugation and Labeling: The reactive carboxyl and protected amine groups allow for site-specific modifications of peptides and proteins.
• Research & Development: Employed in academic and industrial labs for studying protein structure-function relationships and developing new biomolecules.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new bioactive compounds.

Basic Information

Product Name	Ddz-Gln-Oh
CAS No.	88499-14-3
Molecular Formula	C₁₆H₂₂N₂O₅
Molecular Weight	322.36 g/mol
Synonyms	N-[(1,1-Dimethylethoxy)carbonyl]-L-glutamine; N-Boc-L-glutamine; Boc-Gln-OH; (S)-2-((tert-Butoxycarbonyl)amino)-5-aminopentanoic acid; Boc-L-glutamine; N-tert-Butoxycarbonyl-L-glutamine; N-Boc-glutamine; L-Glutamine, N-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our Ddz-Gln-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-15.0° to -18.0° (c=1 in AcOH)
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.