Description

N(6)-Acetyl-N(6)-Hydroxylysine is a chemically modified derivative of the amino acid lysine, featuring both acetylation and hydroxylation at the N(6) position. This specific modification makes it a valuable biochemical building block and research tool for studying protein interactions, post-translational modifications, and metabolic pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from proteomics to the synthesis of specialized peptides and reference standards.

Application

• Biochemical Research: Used as a key intermediate or reference standard in studies of lysine acetylation and hydroxylation, critical processes in epigenetics and cell signaling.
• Pharmaceutical Development: Serves as a building block for the synthesis of novel peptide-based drug candidates and diagnostic agents.
• Proteomics & Metabolomics: Employed as a standard in mass spectrometry and chromatography for the identification and quantification of modified amino acids in complex biological samples.
• Enzyme Substrate Studies: Acts as a substrate for enzymes like lysine hydroxylases and deacetylases to investigate enzyme kinetics and inhibition.
• Nutritional Science Research: Used in metabolic studies to understand the fate and function of modified amino acids in biological systems.
• Quality Control Standards: Provides a high-purity reference material for analytical laboratories to calibrate equipment and validate methods for amino acid analysis.

Basic Information

Product Name	N(6)-Acetyl-N(6)-Hydroxylysine
CAS No.	88492-29-9
Molecular Formula	C8H16N2O4
Molecular Weight	204.22 g/mol
Synonyms	N6-Acetyl-N6-hydroxylysine; N(ε)-Acetyl-N(ε)-hydroxylysine; Acetylhydroxylysine; 2-Amino-6-(acetamidooxy)hexanoic acid; 6-(N-Acetyl-N-hydroxyamino)-L-norleucine; L-Lysine, N6-acetyl-N6-hydroxy-; (2S)-2-Amino-6-[(acetyloxy)amino]hexanoic acid
EINECS	Contact for details

Quality Control

Our N(6)-Acetyl-N(6)-Hydroxylysine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.