Description

Enkephalin-Leu, Ala(2)-(Cyclopropyl-Phe)(4)- CAS NO 88466-08-4 is a synthetic peptide analog of the endogenous opioid peptide enkephalin, featuring strategic amino acid substitutions including cyclopropyl-phenylalanine. This compound is of significant interest in advanced biochemical and pharmacological research due to its potential for enhanced metabolic stability and receptor selectivity compared to native sequences. It is primarily utilized by research institutions and pharmaceutical development teams focused on neuroscience, pain management, and novel therapeutic agent discovery.

Application

• Neuroscience Research: Used as a tool compound to study opioid receptor (delta and mu) signaling pathways and functions.
• Drug Discovery & Development: Serves as a key intermediate or reference standard in the design of novel analgesic and neuroprotective agents.
• Biochemical Assays: Employed in competitive binding assays and enzyme studies to evaluate peptide-receptor interactions.
• Structure-Activity Relationship (SAR) Studies: Critical for investigating the impact of cyclopropyl and other modifications on peptide potency and stability.
• Academic & Institutional Research: Supports fundamental research in neurochemistry, peptide chemistry, and molecular pharmacology.

Basic Information

Product Name	Enkephalin-Leu, Ala(2)-(Cyclopropyl-Phe)(4)-
CAS No.	88466-08-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	[Leu5]Enkephalin, Ala(2)-(Cyclopropyl-Phe)(4)- analog; (2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-Amino-3-cyclopropylpropanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-5-guanidino-N-[(2S,3S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]pentanamide; Cyclopropyl-Phe4, Leu5-Enkephalin analog; Opioid peptide research compound 88466-08-4
EINECS	Contact for details

Quality Control

Our Enkephalin-Leu, Ala(2)-(Cyclopropyl-Phe)(4)- is produced under stringent conditions to ensure high purity and batch-to-batch consistency suitable for research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and NMR. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.