Description

Enkephalin-Leu, Ala(2)-Melphalan Methyl Ester is a specialized synthetic peptide derivative designed for advanced research and development. This compound is of significant interest for its potential role in targeted drug delivery and therapeutic applications, combining structural elements of bioactive peptides with a chemotherapeutic agent. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology and peptide-based therapeutics.

Application

• Pharmaceutical Research: As a key intermediate or active component in the development of novel targeted cancer therapies and prodrug systems.
• Bioconjugation Studies: For investigating peptide-drug conjugates (PDCs) to enhance tumor specificity and reduce systemic toxicity.
• Mechanistic Studies: Used in biochemical and pharmacological research to study drug action mechanisms, receptor binding, and cellular uptake pathways.
• Analytical Standard: Serves as a high-purity reference standard for method development and quality control in analytical laboratories.
• Preclinical Development: For in vitro and in vivo efficacy and safety profiling of new therapeutic candidates.

Basic Information

Product Name	Enkephalin-Leu, Ala(2)-Melphalan Methyl Ester
CAS No.	88457-22-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ala(2)-Melphalan Methyl Ester Enkephalin-Leu; Leu-Enkephalin-Ala(2)-Melphalan Methyl Ester; L-Alanyl-L-leucyl-L-tyrosylglycylglycyl-4-[bis(2-chloroethyl)amino]-L-phenylalanyl-L-alanine methyl ester; Melphalan-Enkephalin Conjugate Methyl Ester; Peptide-Drug Conjugate 88457-22-1; Targeted Chemotherapeutic Peptide; [Leu]Enkephalin-Ala-Melphalan-OMe
EINECS	Contact for details

Quality Control

Our Enkephalin-Leu, Ala(2)-Melphalan Methyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, controlled environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.