Description

Calcitonin, Salmon, Gly(8)- CAS NO 88433-78-7 is a synthetic analog of salmon calcitonin, a polypeptide hormone. This compound is of significant interest for its potent biological activity in regulating calcium and phosphate metabolism in the body. It is primarily utilized in pharmaceutical research and development for metabolic bone disorders, serving as a critical reference standard and active pharmaceutical ingredient (API) intermediate for researchers and manufacturers in the global life sciences sector.

Application

• Pharmaceutical Research & Development: Used as a reference standard and key intermediate in the development of therapeutic agents for osteoporosis, Paget's disease, and hypercalcemia.
• Biochemical Research: Employed in studies investigating calcium homeostasis, bone resorption mechanisms, and endocrine signaling pathways.
• Analytical Standard: Serves as a high-purity calibrant in chromatographic (HPLC, LC-MS) and spectroscopic analyses for quality control and method validation.
• Peptide Synthesis: Acts as a building block or a model compound in the synthesis and structure-activity relationship (SAR) studies of related peptide hormones.

Basic Information

Product Name	Calcitonin, Salmon, Gly(8)- CAS NO 88433-78-7
CAS No.	88433-78-7
Molecular Formula	C₁₄₅H₂₄₀N₄₄O₄₈
Molecular Weight	~3431.8 g/mol
Synonyms	Gly(8)-Calcitonin (salmon); [Gly8]-sCT; Salmon Calcitonin Gly8 analog; Calcitonin (salmon) Glycine-8; UNII-1VB9K96P6G; 1VB9K96P6G; Asparaginyl-L-seryl-L-asparaginyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparaginyl-L-threonyl-glycyl-L-seryl-glycyl-L-threonyl-L-prolylamide (Disulfide bond: Cys7-Cys22)
EINECS	Contact for details

Quality Control

Our Calcitonin, Salmon, Gly(8)- is produced and tested under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or desiccant after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Biological Activity	Assessed by in vitro assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.