Description

5-(Phenylmethoxy)-L-Norvaline is a non-proteinogenic amino acid derivative featuring a benzyl-protected side-chain hydroxyl group. This compound serves as a crucial chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive peptides. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for creating novel therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide-based drugs and protease inhibitors.
• Biochemical Research: Used in studies of amino acid metabolism and as a substrate analog in enzymatic assays.
• Peptide Synthesis: Incorporated into custom peptides to modulate solubility, stability, and biological activity.
• Medicinal Chemistry: Serves as a building block for creating compound libraries in drug discovery programs.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in the preparation of enantiomerically pure compounds.

Basic Information

Product Name	5-(Phenylmethoxy)-L-Norvaline
CAS No.	88403-99-0
Molecular Formula	C₁₃H₁₉NO₃
Molecular Weight	237.29 g/mol
Synonyms	L-2-Amino-5-(benzyloxy)pentanoic acid; (S)-2-Amino-5-(benzyloxy)pentanoic acid; O-Benzyl-L-homoserine; 5-(Benzyloxy)-L-norvaline; L-Norvaline, 5-(phenylmethoxy)-; 5-O-Benzyl-L-homoserine; (S)-5-(Benzyloxy)norvaline; 2-Amino-5-(benzyloxy)pentanoic acid, L-
EINECS	Contact for details

Quality Control

Our 5-(Phenylmethoxy)-L-Norvaline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.