Description

Bovine Parathyroid Hormone (35-84) is a specific, bioactive fragment of the native parathyroid hormone (PTH). This peptide is crucial for research into calcium and phosphate metabolism, bone biology, and endocrine signaling pathways. It serves as a vital biochemical tool for scientists and developers in pharmaceutical research, academic biochemistry, and diagnostic assay development, particularly for studying PTH receptor interactions and metabolic disorders.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of parathyroid hormone function, calcium homeostasis, and bone remodeling mechanisms.
• Receptor Binding Assays: Essential for competitive binding studies and characterization of PTH/PTHrP receptor (PTH1R) affinity and activation.
• Cell Signaling Studies: Applied in vitro to investigate intracellular signaling cascades (e.g., cAMP production) triggered by PTH receptor activation.
• Diagnostic Development: Serves as a calibrant or antigen in the development and validation of immunoassays for PTH-related analytes.
• Peptide Chemistry Reference: Used as a standard in chromatographic (HPLC) and mass spectrometric analyses for method development and quality control of related peptides.
• Academic & Educational Use: Employed in university and institutional laboratories for teaching advanced endocrinology and peptide hormone biology.

Basic Information

Product Name	Bovine Parathyroid Hormone (35-84)
CAS No.	88394-46-1
Molecular Formula	C₂₂₅H₃₆₈N₇₂O₆₈S₂
Molecular Weight	~5250.9 g/mol
Synonyms	Parathyroid Hormone (35-84), bovine; PTH (35-84); bPTH(35-84); Parathyrin (35-84); Parathormone fragment 35-84; Bovine PTH mid-region fragment; N-terminal truncated PTH; CAS 88394-46-1
EINECS	Contact for details

Quality Control

Our Bovine Parathyroid Hormone (35-84) is produced and handled under strict quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Our quality system is designed to deliver high consistency and reliability for critical experimental work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Biological Activity	Assessed by in vitro cAMP assay (Data on COA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.