Description

Glucagon (1-17) is a bioactive peptide fragment derived from the N-terminal sequence of the full-length glucagon hormone. This compound is of significant interest for its role in metabolic research and as a key intermediate in the development of peptide-based pharmaceuticals. It serves as a critical tool for researchers and manufacturers in the fields of endocrinology, diabetes research, and peptide synthesis. The product is supplied as a high-purity material to ensure reliable and reproducible results in demanding applications.

Application

• Biochemical Research: Used as a reference standard and active agent in studies investigating glucagon receptor binding, signal transduction, and metabolic pathways.
• Pharmaceutical Intermediates: Serves as a key building block in the solid-phase or solution-phase synthesis of longer glucagon analogs and related peptide therapeutics.
• Diagnostic Development: Employed in the development and calibration of immunoassays (ELISA, RIA) for glucagon detection and metabolic disorder diagnostics.
• Structure-Activity Relationship (SAR) Studies: Essential for mapping the bioactive regions of glucagon to design novel agonists or antagonists with modified properties.
• Academic & Institutional Laboratories: Provides a defined, high-quality peptide for teaching and advanced research in peptide chemistry and hormone biology.

Basic Information

Product Name	Glucagon (1-17)
CAS No.	88389-49-5
Molecular Formula	C98H150N28O29S
Molecular Weight	2248.5 g/mol
Synonyms	Glucagon Fragment 1-17; H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-OH; HGEGTFTSDYSKYLDSR; Glucagon (1-17) amide (parent compound); N-Terminal Glucagon Peptide
EINECS	Contact for details

Quality Control

Our Glucagon (1-17) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets high-grade research standards. Certificates of Analysis (COA) detailing purity, peptide content, and related substance profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.