Description

Cyclo(Glycyl-Alanyl-Valyl-Leucyl-Isoleucyl) CAS NO 88364-69-6 is a synthetic cyclic pentapeptide composed of the amino acids glycine, alanine, valine, leucine, and isoleucine. This compound is of significant interest in biochemical and pharmaceutical research due to its constrained structure, which serves as a valuable model for studying peptide conformation, stability, and receptor interactions. It is primarily utilized by research institutions and pharmaceutical development companies engaged in peptide chemistry, drug discovery, and the development of novel bioactive molecules.

Application

• Biochemical Research: Used as a reference standard and model compound for studying cyclic peptide conformation, folding, and stability under various conditions.
• Pharmaceutical Development: Serves as a key intermediate or scaffold in the discovery and synthesis of novel peptide-based therapeutics and drug candidates.
• Protease Inhibition Studies: Investigated for its potential as a protease inhibitor due to its constrained cyclic structure, which can mimic enzyme substrates.
• Material Science: Explored for the development of advanced biomaterials and self-assembling nanostructures based on peptide architectures.
• Academic & Industrial R&D: Employed in universities and corporate R&D labs for fundamental research in organic synthesis, medicinal chemistry, and biophysics.

Basic Information

Product Name	Cyclo(Glycyl-Alanyl-Valyl-Leucyl-Isoleucyl)
CAS No.	88364-69-6
Molecular Formula	C22H38N6O5
Molecular Weight	466.57 g/mol
Synonyms	Cyclo(Gly-Ala-Val-Leu-Ile); Cyclo(GAVLI); c(GAVLI); Cyclic Pentapeptide GAVLI; Cyclo(Glycyl-L-alanyl-L-valyl-L-leucyl-L-isoleucyl); L-Isoleucyl-L-leucyl-L-valyl-L-alanylglycine cyclic pentapeptide; Cyclo(Glycine-L-alanine-L-valine-L-leucine-L-isoleucine); Cyclo(Gly-Ala-Val-Leu-Ile-OH)
EINECS	Contact for details

Quality Control

Our Cyclo(Glycyl-Alanyl-Valyl-Leucyl-Isoleucyl) is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity determination, mass spectrometry for identity confirmation, and chiral analysis to verify stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.