Description

Medorinone is a high-purity pharmaceutical intermediate and research chemical with significant biological activity. This compound is of critical importance for the development and synthesis of novel therapeutic agents, particularly in cardiovascular research. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the production of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced cardiovascular drug candidates.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies to investigate phosphodiesterase (PDE) inhibition.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structure for the development of new inotropic agents aimed at treating heart failure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Employed in university and institutional labs for studying cardiac muscle contractility and related metabolic pathways.

Basic Information

Product Name	Medorinone
CAS No.	88296-61-1
Molecular Formula	C12H9N3O2
Molecular Weight	227.22 g/mol
Synonyms	1,6-Dihydro-2-methyl-6-oxo-3,4'-bipyridine-5-carbonitrile; 4-(5-Cyano-4-methyl-2-oxo-1,6-dihydropyridin-3-yl)pyridine; 3,4'-Bipyridine-5-carbonitrile, 1,6-dihydro-2-methyl-6-oxo-; Medorinon; AR-L 115 BS
EINECS	Contact for details

Quality Control

Our Medorinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.