Description

n-(2,2-Dimethylpropanoyl)-2-Fluoroaniline is a specialized fluorinated aniline derivative, serving as a high-value building block in advanced organic synthesis. Its core value lies in its unique molecular structure, which combines a sterically hindered pivaloyl group with a fluorine-substituted aromatic amine, enabling precise modifications in target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with specific electronic or surface properties.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological mechanisms and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	n-(2,2-Dimethylpropanoyl)-2-Fluoroaniline
CAS No.	88288-07-7
Molecular Formula	C13H16FNO
Molecular Weight	221.27 g/mol
Synonyms	2-Fluoro-N-pivaloylaniline; N-Pivaloyl-2-fluoroaniline; 2-Fluoro-N-(2,2-dimethylpropanoyl)aniline; Pivalanilide, 2'-fluoro-; 2'-Fluoropivalanilide; N-(2,2-Dimethyl-1-oxopropyl)-2-fluoroaniline; 2-Fluoro-N-(2,2-dimethylpropionyl)aniline; 88288-07-7
EINECS	Contact for details

Quality Control

Our n-(2,2-Dimethylpropanoyl)-2-Fluoroaniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-aligned production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.