Description

Enkephalin-Leu, N,n-Diallyl-Ala(2)- is a chemically modified peptide analog of the endogenous opioid peptide Leu-enkephalin. This compound is of significant interest for advanced biochemical and pharmacological research, particularly in the study of opioid receptor interactions and signal transduction pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuroscience, pain management research, and novel drug discovery programs.

Application

• Neuroscience Research: As a tool compound for investigating the structure-activity relationships (SAR) of opioid peptides and their receptors.
• Pharmacological Studies: Used in in vitro and in vivo assays to study analgesia, tolerance, and dependence mechanisms related to the opioid system.
• Drug Discovery: Serves as a key intermediate or reference standard in the development of novel analgesic or neuroprotective agents with potentially improved profiles.
• Biochemical Assays: Employed in receptor binding studies and functional assays (e.g., cAMP inhibition, GTPγS binding) to characterize receptor subtype selectivity and efficacy.
• Academic Research: A valuable reagent for universities and research institutes exploring neuropeptide chemistry, peptide modification strategies, and central nervous system (CNS) drug targets.

Basic Information

Product Name	Enkephalin-Leu, N,n-Diallyl-Ala(2)-
CAS No.	88285-66-9
Molecular Formula	C31H48N6O7
Molecular Weight	616.75 g/mol
Synonyms	N,N-Diallyl-Ala(2)-Leu-enkephalin; [D-Ala2, N,N-Diallyl]-Leu-enkephalin; H-Tyr-D-Ala(N,N-Diallyl)-Gly-Phe-Leu-OH; Leu5-Enkephalin, [D-Ala2, N,N-Diallyl]-; Opioid peptide analog 88285-66-9; DADALE; N,N-Diallyl-D-alanine2-leucine-enkephalin
EINECS	Contact for details

Quality Control

Our Enkephalin-Leu, N,n-Diallyl-Ala(2)- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research-grade biochemicals, ensuring reliable performance in your experimental systems.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability. Allow the vial to equilibrate to room temperature in a dry atmosphere before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.