Description

Dithiobis[2-Amino-4-Methylpentane] Dihydrochloride is a specialized organic sulfur compound primarily used as a key intermediate in the synthesis of more complex molecules. Its value lies in its unique disulfide bridge and protected amine functionality, which are critical for constructing peptides, modifying biomolecules, and creating specialized ligands. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable building blocks for advanced synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting disulfide-rich proteins or requiring specific molecular scaffolds.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce disulfide bonds or as a protected cysteine analogue, enabling the creation of stable, structured peptides.
• Bioconjugation Reagent: Facilitates the site-specific cross-linking or labeling of proteins, antibodies, and other biomolecules for diagnostic and therapeutic applications.
• Chemical Research: Serves as a versatile reagent in organic synthesis for constructing heterocycles, complex ligands for catalysis, and functional materials.
• Protecting Group Strategy: The dihydrochloride salt form provides a stable, protected intermediate for multi-step synthetic sequences where amine functionality must be masked and later revealed.

Basic Information

Product Name	Dithiobis[2-Amino-4-Methylpentane] Dihydrochloride
CAS No.	88264-65-7
Molecular Formula	C₁₂H₂₈N₂S₂·2HCl
Molecular Weight	337.40 g/mol
Synonyms	L-Cystine di-tert-butyl ester dihydrochloride; (R,R)-2,2'-(Dithiodi-2,1-phenylene)bis(2-methylpropane) dihydrochloride; Bis(2-amino-4-methylpentane) disulfide dihydrochloride; 2,2'-Dithiobis(4-methyl-2-aminopentane) dihydrochloride; DTB-L-Cystine·2HCl; tert-Butyl S-trityl-L-cysteinate disulfide dihydrochloride (related derivative); Leucine-based disulfide dihydrochloride
EINECS	Contact for details

Quality Control

Our Dithiobis[2-Amino-4-Methylpentane] Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.