Description

n-Acetyl-α-Endorphin is a chemically modified analog of the endogenous neuropeptide α-endorphin. This modification enhances its stability and bioavailability, making it a valuable tool for advanced biochemical and pharmacological research. It is primarily utilized by research institutions and pharmaceutical developers in neuroscience, peptide chemistry, and drug discovery programs.

Application

• Neuroscience Research: Used as a reference standard or active agent in studies investigating opioid receptor pathways, pain modulation, and neurobehavioral effects.
• Biochemical Assay Development: Serves as a critical component in developing and validating assays for endorphin activity and receptor binding studies.
• Pharmaceutical R&D: Employed in preclinical research for exploring novel analgesic or neuroprotective drug candidates based on endorphin analogs.
• Peptide Chemistry Studies: Used to study the structure-activity relationships (SAR) of acetylated peptides and their metabolic stability.
• Academic Research: A key reagent for university laboratories focusing on neuropeptides, psychopharmacology, and molecular biology.

Basic Information

Item	Detail
Product Name	n-Acetyl-α-Endorphin
CAS No.	88264-63-5
Molecular Formula	C89H134N22O26S
Molecular Weight	1992.2 g/mol
Synonyms	Ac-α-Endorphin; N-Acetyl-α-endorphin; N-Acetyl-α-endorphin; Acetylated α-Endorphin; α-Endorphin, N-acetyl-; L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-threonyl-L-seryl-L-glutamyl-L-lysyl-L-seryl-L-glutaminyl-L-threonyl-L-prolyl-L-leucyl-L-valyl-L-threonyl-L-leucine, N-acetyl-; Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu, N-acetyl-
EINECS	Contact for details

Quality Control

Every batch of n-Acetyl-α-Endorphin is manufactured and tested under stringent quality management systems. We provide comprehensive analytical data to support your research, including purity verification by HPLC and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and content is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.