Description

Vasopressin, 1-Penicillamine-2-o-Metyr-8-Lys- is a synthetic peptide analog of the endogenous hormone vasopressin, specifically engineered with amino acid substitutions to modulate its receptor binding profile and metabolic stability. This compound is of significant interest for advanced research and development in endocrinology and cardiovascular pharmacology. It serves as a critical tool for scientists and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) in the development of novel vasopressin receptor agonists or antagonists.
• Biochemical Studies: For investigating the structure-activity relationships (SAR) of vasopressin analogs and their interaction with V1a, V1b, and V2 receptors.
• Preclinical Modeling: Utilized in animal models to study cardiovascular function, renal water reabsorption, and central nervous system effects.
• Diagnostic Agent Development: Potential use in the formulation of diagnostic kits for endocrine disorders related to vasopressin pathway dysregulation.
• Peptide Chemistry & Process Development: Serves as a model compound for optimizing solid-phase peptide synthesis (SPPS) and purification techniques for complex peptides.

Basic Information

Product Name	Vasopressin, 1-Penicillamine-2-o-Metyr-8-Lys-
CAS No.	88210-91-7
Molecular Formula	C46H65N13O12S2
Molecular Weight	1040.2 g/mol
Synonyms	[1-β-Mercapto-β,β-cyclopentamethylenepropionic acid, 2-O-methyltyrosine, 8-lysine]vasopressin; d(CH2)5[Tyr(Me)2,Lys8]VP; Desmopressin analog; V1a-receptor antagonist; 1-Pen,2-O-Me-Tyr,8-Lys-Vasopressin; (1-β-Mercapto-β,β-cyclopentamethylenepropionic acid)-2-O-methyltyrosine-8-lysine-vasopressin; Manning Compound; SK&F 105494
EINECS	Contact for details

Quality Control

Our Vasopressin, 1-Penicillamine-2-o-Metyr-8-Lys- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. Due to its hygroscopic (moisture-sensitive) nature, the product should be handled in a dry environment and allowed to equilibrate to room temperature before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 5.0%
Peptide Content (AAA)	≥ 80.0%
Solubility	Soluble in water, acetic acid; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.