Description

Ancovenin CAS NO 88201-41-6 is a bioactive peptide compound of significant interest in biochemical research and pharmaceutical development. Its primary value lies in its specific inhibitory activity against angiotensin-converting enzyme (ACE), making it a crucial tool for studying cardiovascular regulation and hypertension pathways. This compound is essential for researchers and developers in the pharmaceutical, biotechnology, and life science sectors who are engaged in drug discovery, enzyme kinetics studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of cardiovascular drugs, particularly ACE inhibitors.
• Biochemical Assays: Used as a specific substrate or inhibitor in in vitro enzymatic assays to study ACE activity, mechanism of action, and inhibition kinetics.
• Life Science Research: A vital tool in academic and industrial laboratories for investigating the renin-angiotensin system, blood pressure regulation, and related metabolic pathways.
• Peptide Chemistry Studies: Employed in structural-activity relationship (SAR) studies to understand the interaction between peptide sequences and enzyme active sites.
• Quality Control & Standardization: Acts as a certified reference material (CRM) for the quality control and validation of analytical methods in pharmaceutical manufacturing.

Basic Information

Item	Detail
Product Name	Ancovenin
CAS No.	88201-41-6
Molecular Formula	C41H62N12O11
Molecular Weight	875.0 g/mol (approx.)
Synonyms	Ancovenin; ACE Inhibitory Peptide; Angiotensin I-Converting Enzyme Inhibitor (Ancovenin); L-Leucyl-L-valyl-L-α-aspartyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-prolyl-L-proline; H-Leu-Val-Asp-Asp-Trp-Pro-Glu-Glu-Ile-Pro-Pro-OH; Peptide Ancovenin.
EINECS	Contact for details

Quality Control

Our Ancovenin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity determination by high-performance liquid chromatography (HPLC). A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Biological Activity (ACE Inhibition)	Conforms to reference (IC50 provided on COA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.