Description

6-Chloro-4-Phenyl-3, 4-Dihydroquinazoline-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic quinazoline core structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazoline-based drug candidates, particularly for oncology and central nervous system (CNS) applications.
• Agrochemical Research: Serves as a scaffold for developing new herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Synthesis: Used in organic synthesis to construct complex heterocyclic systems for material science and catalysis research.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard in pharmacological studies targeting specific enzymes or receptors.
• Academic & Industrial R&D: Essential for medicinal chemistry programs in both academic laboratories and industrial R&D departments for lead optimization and structure-activity relationship (SAR) studies.

Basic Information

Product Name	6-Chloro-4-Phenyl-3, 4-Dihydroquinazoline-2-Carboxylic Acid
CAS No.	88190-77-6
Molecular Formula	C15H11ClN2O2
Molecular Weight	286.71 g/mol
Synonyms	2-Quinazolinecarboxylic acid, 6-chloro-3,4-dihydro-4-phenyl-; 6-Chloro-4-phenyl-3,4-dihydro-2-quinazolinecarboxylic acid; 4-Phenyl-6-chloro-3,4-dihydroquinazoline-2-carboxylic acid; 88190-77-6; 6-Chloro-4-phenyl-1,2,3,4-tetrahydroquinazoline-2-carboxylic acid; Quinazoline-2-carboxylic acid, 6-chloro-3,4-dihydro-4-phenyl-
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Phenyl-3, 4-Dihydroquinazoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.