Description

2(1H)-Pyrimidinone,1-(2-Propynyl)-(9Ci) CAS NO 88167-35-5 is a specialized heterocyclic organic compound featuring a pyrimidinone core functionalized with a propargyl group. This unique structure makes it a valuable high-purity building block for advanced chemical synthesis, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients. The compound's propargyl moiety offers a versatile handle for further chemical modifications via click chemistry and other coupling reactions.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: The alkyne group enables its use as a probe or tag in bioorthogonal labeling strategies for studying biological processes.
• Material Science Research: Investigated as a monomer or functional additive for creating advanced polymers with specific thermal or electronic properties.
• Academic & Industrial R&D: A crucial reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Item	Details
Product Name	2(1H)-Pyrimidinone,1-(2-Propynyl)-(9Ci)
CAS No.	88167-35-5
Molecular Formula	C7H6N2O
Molecular Weight	134.14 g/mol
Synonyms	1-Propargylpyrimidin-2(1H)-one; 1-(Prop-2-yn-1-yl)pyrimidin-2(1H)-one; 1-(2-Propynyl)-2(1H)-pyrimidinone; 2-Hydroxy-1-propargylpyrimidine; N-Propargyl-2-pyrimidone; 88167-35-5; 1-(Prop-2-ynyl)pyrimidin-2-ol
EINECS	Contact for details

Quality Control

We supply 2(1H)-Pyrimidinone,1-(2-Propynyl)-(9Ci) in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with stringent internal specifications. Standard analytical techniques including HPLC, GC, NMR, and mass spectrometry are employed. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic). For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.