Description

(2,3-Dihydroxybenzoyl)-L-Alanyl-L-Threonine is a specialized dipeptide derivative featuring a catechol moiety, offering unique chelating and bioactive properties. This compound is valued for its role as a key intermediate in the synthesis of complex siderophore analogs and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, microbiology, and the development of novel chelation therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of siderophore-mimetic drugs and antimicrobial conjugates.
• Microbiological Research: Used in studies of iron acquisition pathways and the development of novel antibiotics targeting bacterial iron transport systems.
• Chelation Agent Development: Acts as a precursor for designing new ligands with high affinity for specific metal ions (e.g., Fe³⁺, Al³⁺).
• Bioconjugation Chemistry: Employed in the creation of targeted drug delivery systems where the catechol group facilitates attachment to nanoparticles or other carriers.
• Enzyme Inhibition Studies: Investigated for its potential to inhibit enzymes involved in bacterial virulence or metal homeostasis.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(2,3-Dihydroxybenzoyl)-L-Alanyl-L-Threonine
CAS No.	88167-28-6
Molecular Formula	C₁₄H₁₈N₂O₇
Molecular Weight	326.30 g/mol
Synonyms	N-(2,3-Dihydroxybenzoyl)-L-alanyl-L-threonine; L-Alanyl-L-threonine, N-(2,3-dihydroxybenzoyl)-; 2,3-DHB-L-Ala-L-Thr; Catecholamide dipeptide; Siderophore fragment; (2,3-DHB)-Ala-Thr; N-(2,3-Dihydroxybenzoyl)alanylthreonine
EINECS	Contact for details

Quality Control

Our (2,3-Dihydroxybenzoyl)-L-Alanyl-L-Threonine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation and moisture. Allow the container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.