Description

2,4-Dihydroxyl-6-Fluoroquinazoline is a fluorinated quinazoline derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of high-value active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily needed by research and production teams in the pharmaceutical, agrochemical, and material science industries seeking to incorporate its unique fluorinated quinazoline scaffold into novel molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of tyrosine kinase inhibitors and other targeted cancer therapeutics.
• Agrochemical Research: Used in developing novel herbicides and fungicides that leverage the biological activity of the quinazoline core.
• Fine Chemical Synthesis: Serves as a building block for creating complex fluorinated heterocycles for various specialty applications.
• Material Science: Investigated for use in the development of organic electronic materials and advanced polymers.
• Biochemical Research: Employed as a standard or reagent in studies involving enzyme inhibition and molecular modeling.

Basic Information

Product Name	2,4-Dihydroxyl-6-Fluoroquinazoline
CAS No.	88145-90-8
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	6-Fluoro-2,4-dihydroxyquinazoline; 6-Fluoro-2,4(1H,3H)-quinazolinedione; 2,4-Dihydroxy-6-fluoroquinazoline; 6-Fluoroquinazoline-2,4-diol; 88145-90-8; 6-Fluoro-2,4-dihydroxy-1,3-diazanaphthalene; Fluoroquinazolinedione
EINECS	Contact for details

Quality Control

Our 2,4-Dihydroxyl-6-Fluoroquinazoline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.