Description

4-Bromo-3-(Difluoromethoxy)Aniline is a versatile halogenated aniline derivative, distinguished by its bromine and difluoromethoxy substituents. This compound serves as a critical pharmaceutical intermediate and agrochemical building block, enabling the synthesis of complex molecules with enhanced biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting novel therapeutics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for specialty chemicals used in electronic displays and organic light-emitting diodes.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and colorants for high-performance applications.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for creating complex aromatic amines.
• Research & Development: Essential for academic and industrial research in organic chemistry and medicinal chemistry.

Basic Information

Product Name	4-Bromo-3-(Difluoromethoxy)Aniline
CAS No.	87967-37-1
Molecular Formula	C7H6BrF2NO
Molecular Weight	238.03 g/mol
Synonyms	4-Bromo-3-(difluoromethoxy)benzenamine; 3-(Difluoromethoxy)-4-bromoaniline; Benzenamine, 4-bromo-3-(difluoromethoxy)-; 4-Bromo-3-difluoromethoxyaniline; 4-Bromo-α,α-difluoro-m-anisidine
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-3-(Difluoromethoxy)Aniline adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.