Description

((R)-4-Hydroxy-4-Methyl-Orn)-Phalloidin is a chemically modified derivative of the potent cyclic heptapeptide toxin, phalloidin. This compound is of significant value in biochemical and pharmacological research due to its specific interaction with actin filaments. It is primarily utilized by researchers in life sciences, toxicology, and drug discovery who require high-purity, well-characterized molecular probes for studying cytoskeletal dynamics and cellular mechanisms.

Application

• Biochemical Research: As a specialized molecular probe for investigating the structure and function of F-actin in vitro.
• Cytoskeleton Studies: For labeling and visualizing actin filaments in fixed cell preparations using fluorescence microscopy techniques.
• Pharmacology & Toxicology: Serving as a reference standard or tool compound in studies of toxin mechanisms and the development of potential antidotes.
• Drug Discovery Platforms: Used in high-content screening assays to identify compounds that affect actin polymerization or depolymerization.
• Academic & Institutional Research: A critical reagent for fundamental research in cell biology, biophysics, and structural biology.

Basic Information

Product Name	((R)-4-Hydroxy-4-Methyl-Orn)-Phalloidin
CAS No.	87876-22-0
Molecular Formula	C36H51N7O11S
Molecular Weight	789.91 g/mol
Synonyms	Phalloidin, (R)-4-Hydroxy-4-methylornithine derivative; 4-Hydroxy-4-methyl-L-ornithine-phalloidin; (4R)-4-Hydroxy-4-methyl-L-ornithine7-phalloidin; Modified Phalloidin derivative; Actin-binding probe; Cyclic heptapeptide toxin analog; Amanita phalloides toxin derivative
EINECS	Contact for details

Quality Control

Our ((R)-4-Hydroxy-4-Methyl-Orn)-Phalloidin is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity by HPLC, identity confirmation by mass spectrometry, and other relevant parameters are provided to guarantee it meets the exacting standards required for scientific research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be kept under desiccated conditions. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.