Description

Ethyl 2,4,6-Trichloropyrimidine-5-Carboxylate is a high-purity, multi-functional pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its versatile reactivity, particularly as a key precursor for the development of complex heterocyclic compounds, including active pharmaceutical ingredients (APIs) and agrochemicals. This intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of various drug candidates, particularly those with pyrimidine-based cores, such as kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trichloropyrimidine moiety.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and developing novel synthetic methodologies.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Product Name	Ethyl 2,4,6-Trichloropyrimidine-5-Carboxylate
CAS No.	87848-14-4
Molecular Formula	C7H5Cl3N2O2
Molecular Weight	255.48 g/mol
Synonyms	Ethyl 2,4,6-Trichloro-5-pyrimidinecarboxylate; 2,4,6-Trichloropyrimidine-5-carboxylic Acid Ethyl Ester; 5-Carbethoxy-2,4,6-trichloropyrimidine; 5-(Ethoxycarbonyl)-2,4,6-trichloropyrimidine; Ethyl 2,4,6-Trichloro-5-Pyrimidinecarboxylate; 2,4,6-Trichloro-5-pyrimidinecarboxylic acid ethyl ester; 5-Ethoxycarbonyl-2,4,6-trichloropyrimidine
EINECS	Contact for details

Quality Control

Our Ethyl 2,4,6-Trichloropyrimidine-5-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; ensure containers are kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.