Description

5-Benzyloxy-2-(1-Piperazinyl)Pyrimidine is a high-purity, functionalized pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a benzyloxy and a piperazinyl substituent, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Chemical Research & Development: Used as a sophisticated scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and pesticides.
• Academic Research: Employed in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals for clients.

Basic Information

Product Name	5-Benzyloxy-2-(1-Piperazinyl)Pyrimidine
CAS No.	87789-61-5
Molecular Formula	C15H18N4O
Molecular Weight	270.33 g/mol
Synonyms	2-(Piperazin-1-yl)-5-(phenylmethoxy)pyrimidine; 5-(Benzyloxy)-2-(1-piperazinyl)pyrimidine; 5-Benzyloxy-2-piperazin-1-ylpyrimidine; 2-Piperazinyl-5-benzyloxypyrimidine; 5-(Benzyloxy)-2-piperazin-1-yl-pyrimidine; 87789-61-5; 5-Benzyloxy-2-piperazinylpyrimidine
EINECS	Contact for details

Quality Control

Our 5-Benzyloxy-2-(1-Piperazinyl)Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our customers in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.