Description

β-Casomorphin[1-4] Amide Hydrochloride is a synthetic peptide fragment derived from bovine β-casein, specifically the bioactive casomorphin sequence. This compound is of significant interest for its role as a reference standard and research tool in the study of opioid peptides, food-derived bioactive compounds, and neuropharmacology. It is primarily utilized by research institutions, pharmaceutical R&D departments, and analytical laboratories focused on peptide chemistry, food science, and neurobiology.

Application

• Biomedical Research: Used as a high-purity reference standard in studies investigating the opioid activity, receptor binding, and metabolic pathways of casomorphins.
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the research and development of novel peptide-based therapeutics or diagnostic agents.
• Food Science & Safety: Employed in analytical methods to detect, quantify, and study the presence and effects of bioactive peptides in dairy products and infant formulas.
• Neuropharmacology: A critical tool for in vitro and in vivo studies exploring the neurological and behavioral effects of exogenous opioid peptides.
• Analytical Chemistry: Functions as a calibration standard in advanced chromatographic (HPLC, LC-MS) and spectroscopic techniques for method validation and quality control.

Basic Information

Product Name	β-Casomorphin[1-4] Amide Hydrochloride
CAS No.	87777-29-5
Molecular Formula	C24H37N7O7 • HCl
Molecular Weight	572.06 g/mol
Synonyms	β-Casomorphin (1-4) amide hydrochloride; Tyr-Pro-Phe-Pro-NH2 • HCl; β-Casomorphin-4 amide hydrochloride; β-CM-4 amide hydrochloride; YPFPa • HCl; Opioid peptide (bovine, 1-4) amide hydrochloride; H-Tyr-Pro-Phe-Pro-NH2 hydrochloride
EINECS	Contact for details

Quality Control

Our β-Casomorphin[1-4] Amide Hydrochloride is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Quality is verified by multiple orthogonal methods including HPLC, mass spectrometry, and amino acid analysis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.