Description

Tandospirone is a high-purity active pharmaceutical ingredient (API) belonging to the azapirone class of compounds. It is a selective serotonin 5-HT1A receptor partial agonist, primarily valued for its anxiolytic properties. This compound is essential for pharmaceutical R&D and manufacturing, particularly in the development of treatments for anxiety disorders and related central nervous system conditions. Our supply ensures the stringent quality and consistency required for advanced therapeutic applications.

Application

• Primary active pharmaceutical ingredient (API) in anxiolytic drug formulations.
• Key intermediate in the research and synthesis of novel serotonin receptor-targeting therapeutics.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical research tool for studying 5-HT1A receptor pharmacology and signal transduction pathways.
• Preclinical development of treatments for generalized anxiety disorder (GAD).
• Investigational compound for potential applications in depression and other mood-related disorders.

Basic Information

Product Name	Tandospirone
CAS No.	87760-53-0
Molecular Formula	C21H29N5O2
Molecular Weight	383.49 g/mol
Synonyms	Metanopirone; SM-3997; 3aa,4b,7b,7aa-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione; 4-[4-(Pyrimidin-2-yl)piperazin-1-yl]butyl 8-azaspiro[4.5]decane-7,9-dione
EINECS	Contact for details

Quality Control

Our Tandospirone is manufactured under a strict quality management system to meet the exacting standards of pharmaceutical applications. Every batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC. A Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes to ensure compliance with your specifications and regulatory expectations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.