Description

Phyllolitorin, Leu-8- is a synthetic peptide analog of the natural amphibian skin peptide, phyllolitorin. This compound is of significant interest in biochemical and pharmacological research due to its role as a selective ligand for bombesin receptor subtypes. It is primarily utilized by research institutions and pharmaceutical development companies focusing on neuropeptide signaling, receptor characterization, and the development of targeted therapeutic agents.

Application

• Biochemical Research: Used as a standard or probe in studies investigating the structure and function of bombesin-like peptide receptors.
• Pharmacological Studies: Employed in in vitro and in vivo assays to study receptor binding affinity, signal transduction pathways, and physiological effects mediated by neuromedin B receptors.
• Drug Discovery: Serves as a key reference compound or a starting point for the design and synthesis of novel analogs with potential therapeutic applications in oncology or metabolic disorders.
• Neuroscience Research: Applied in research exploring the role of bombesin-related peptides in the central nervous system, including studies on feeding behavior, stress response, and thermoregulation.
• Diagnostic Development: Potential use in the development of receptor-targeted imaging agents or diagnostic assays.

Basic Information

Product Name	Phyllolitorin, Leu-8-
CAS No.	87734-76-7
Molecular Formula	C52H81N15O12
Molecular Weight	1092.3 g/mol
Synonyms	[Leu8]Phyllolitorin; Leu-8-Phyllolitorin; Phyllolitorin (Leu-8); L-Leucine-phyllolitorin; Bombesin-related peptide analog; Neuromedin B receptor agonist; H-Gly-Asn-Trp-Ala-Val-Gly-His-Leu-Met-NH2
EINECS	Contact for details

Quality Control

Our Phyllolitorin, Leu-8- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible and reliable results for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.