Description

3-Amino-3-Demethoxyfortimicin A is a key semi-synthetic derivative and intermediate in the aminoglycoside antibiotic class. This compound is of significant value for pharmaceutical research and development, particularly in the synthesis of novel antimicrobial agents. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing advanced antibiotic therapies to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: A critical building block in the chemical synthesis of novel aminoglycoside antibiotics and their analogs.
• Antimicrobial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) and mechanisms of action against resistant bacteria.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Medicinal Chemistry: Employed in lead optimization programs to develop new therapeutic candidates with improved efficacy and reduced toxicity profiles.

Basic Information

Product Name	3-Amino-3-Demethoxyfortimicin A
CAS No.	87713-59-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fortimicin A, 3-Amino-3-de-O-methyl derivative; 3-Amino-3-demethoxy-fortimicin A; Antibiotic KA-6606 IX; Demethoxyfortimicin A, 3-Amino derivative; (2R,3S,4S,5R,6S)-5-Amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxyoxane-3,4-diol
EINECS	Contact for details

Quality Control

Our 3-Amino-3-Demethoxyfortimicin A is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing all test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.