Description

Pyr-Trp-Oet CAS NO 87694-58-4 is a specialized protected dipeptide derivative, specifically the ethyl ester of pyroglutamyl-tryptophan. This compound serves as a crucial high-purity building block in advanced organic synthesis, particularly for the construction of complex peptides and peptidomimetics. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical manufacturers engaged in developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key precursor in the solid-phase and solution-phase synthesis of peptide-based drug candidates targeting neurological and metabolic disorders.
• Biochemical Research: Used as a standardized reagent for studying enzyme-substrate interactions, particularly with proteases and peptidases.
• Peptidomimetic Development: Essential for creating stable, bioavailable analogs of natural peptides for therapeutic applications.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Cosmeceutical Actives: Potential intermediate in the synthesis of bioactive peptides for advanced skincare formulations.

Basic Information

Product Name	Pyr-Trp-Oet
CAS No.	87694-58-4
Molecular Formula	C₁₉H₂₁N₃O₄
Molecular Weight	355.39 g/mol
Synonyms	L-Pyroglutamyl-L-tryptophan ethyl ester; Pyr-Trp-OEt; 5-Oxo-L-prolyl-L-tryptophan ethyl ester; Ethyl L-pyroglutamyl-L-tryptophanate; Ethyl (2S)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoate; N-(L-Pyroglutamyl)-L-tryptophan ethyl ester; pGlu-Trp-OEt
EINECS	Contact for details

Quality Control

Our Pyr-Trp-Oet is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and Mass Spectrometry. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing all critical quality attributes to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.