Description

H-Tyr-D-Met(O)-Gly-n-Me-Phenylethylamide is a specialized synthetic peptide derivative, primarily utilized as a key intermediate in advanced pharmaceutical research and development. Its modified structure, featuring a sulfoxide group and specific stereochemistry, makes it valuable for studying receptor-ligand interactions and metabolic pathways. This compound is essential for researchers and manufacturers in the fields of peptide-based drug discovery, neuropharmacology, and biochemical assay development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel therapeutic peptides targeting neurological and metabolic disorders.
• Biochemical Research: Used as a reference standard or probe in studies of opioid receptor binding, signal transduction, and enzyme inhibition assays.
• Drug Discovery: Serves as a core structure for the development of new chemical entities (NCEs) with potential analgesic or neuroprotective properties.
• Academic Research: Employed in university and institutional labs for investigating peptide conformation, stability, and structure-activity relationships (SAR).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom peptide synthesis projects under GMP conditions.

Basic Information

Product Name	H-Tyr-D-Met(O)-Gly-n-Me-Phenylethylamide
CAS No.	87636-57-5
Molecular Formula	C23H30N4O5S
Molecular Weight	474.57 g/mol
Synonyms	Tyrosyl-D-methionine sulfoxide-glycyl-N-methylphenethylamide; Dmt-Tic-Oic-OH; H-Tyr-D-Met(O)-Gly-Phe-NHMe; Tyr-D-Met(O)-Gly-ψ[CH2NH]-Phe; Opioid peptide derivative 87636-57-5; n-Me-Phenylethylamide derivative; D-Methionine sulfoxide containing peptide
EINECS	Contact for details

Quality Control

Our H-Tyr-D-Met(O)-Gly-n-Me-Phenylethylamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide Certificates of Analysis (COA) with detailed results for all critical parameters, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled temperature of -20°C or below for long-term stability. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.