Description

Neurotensin (1-6) is a bioactive hexapeptide fragment derived from the endogenous neuropeptide Neurotensin. This compound is a crucial research tool for investigating the structure-activity relationships and biological functions of the full-length neuropeptide. It is primarily utilized by researchers in the fields of neuroscience, pharmacology, and biochemistry. The peptide is valued for its role in studying receptor binding, signal transduction pathways, and potential therapeutic applications.

Application

• Neuroscience Research: Used as a reference standard and tool to study the role of neurotensin in the central nervous system, including its effects on dopamine transmission and behavior.
• Pharmacological Studies: Employed in receptor binding assays and functional studies to characterize neurotensin receptor subtypes (NTS1 and NTS2) and screen for receptor agonists or antagonists.
• Biochemical Research: Serves as a substrate or ligand in enzymatic studies and for understanding peptide-receptor interaction mechanisms.
• Drug Discovery: Acts as a lead compound or molecular scaffold for the development of novel neuropsychiatric drugs targeting neurotensin pathways.
• Academic & Institutional Research: Essential for university and institutional labs conducting fundamental research on neuropeptides and gut-brain axis signaling.
• In vitro Diagnostics (IVD) Development: Potential use in the development of immunoassays or diagnostic kits for research purposes.

Basic Information

Product Name	Neurotensin (1-6)
CAS No.	87620-09-5
Molecular Formula	C33H49N9O9
Molecular Weight	715.81 g/mol
Synonyms	L-Pyroglutamyl-L-leucyl-L-tyrosyl-L-glutamyl-L-asparaginyl-L-lysine; Pyr-Leu-Tyr-Glu-Asn-Lys-OH; NT(1-6); Neurotensin 1-6; H-Pyr-Leu-Tyr-Glu-Asn-Lys-OH; Neurotensin hexapeptide; Glp-Leu-Tyr-Glu-Asn-Lys
EINECS	Contact for details

Quality Control

Our Neurotensin (1-6) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets high-purity research-grade standards. Comprehensive Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.