Description

2-Amino-5-Isopropylbenzotrifluoride is a high-value fluorinated aromatic amine building block, essential for the synthesis of advanced chemical intermediates. Its unique structure, combining an amino group with a trifluoromethyl and an isopropyl substituent, provides significant advantages in modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated properties.
• Dye and Pigment Industry: Acts as an intermediate in the synthesis of specialized dyes and pigments, contributing to color fastness and unique optical properties.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to create complex biaryl amine structures.

Basic Information

Product Name	2-Amino-5-Isopropylbenzotrifluoride
CAS No.	87617-29-6
Molecular Formula	C10H12F3N
Molecular Weight	203.21 g/mol
Synonyms	2-Amino-5-(1-methylethyl)benzotrifluoride; 5-Isopropyl-2-aminobenzotrifluoride; 2-Amino-α,α,α-trifluoro-5-isopropyltoluene; 2-Trifluoromethyl-4-isopropylaniline; 4-Isopropyl-2-(trifluoromethyl)aniline; Benzenamine, 4-(1-methylethyl)-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-4-isopropylaniline
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Isopropylbenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening sealed containers. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.