Description

Pyrimidine, 5-(1-Chloroethenyl)-2-(Methylthio)- (9Ci) is a specialized halogenated and sulfur-containing heterocyclic compound that serves as a high-value synthetic intermediate. Its unique structure, featuring a reactive chloroethenyl group and a methylthio substituent, makes it a critical building block for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the design of chemical probes, affinity labels, and bioconjugation reagents.
• Organic Synthesis & Catalysis: Acts as a versatile scaffold for constructing complex heterocycles and as a ligand precursor in catalytic systems.

Basic Information

Product Name	Pyrimidine, 5-(1-Chloroethenyl)-2-(Methylthio)- (9Ci)
CAS No.	87573-79-3
Molecular Formula	C7H7ClN2S
Molecular Weight	186.66 g/mol
Synonyms	5-(1-Chloroethenyl)-2-(methylthio)pyrimidine; 2-(Methylthio)-5-vinylidenechloropyrimidine; 5-(Chlorovinyl)-2-methylthiopyrimidine; 2-Methylsulfanyl-5-(1-chloroethenyl)pyrimidine; Pyrimidine, 2-(methylthio)-5-(1-chloroethenyl)-; 87573-79-3; 5-(1-Chloroethenyl)-2-methylsulfanylpyrimidine
EINECS	Contact for details

Quality Control

Every batch of Pyrimidine, 5-(1-Chloroethenyl)-2-(Methylthio)- (9Ci) is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. Due to the reactive chloroethenyl group, prolonged storage should be under an inert atmosphere for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.