Description

(Pyr4, Cys-Cys6, Arg8)-Vasopressin*Fragment 4-8 CAS NO 87558-80-3 is a synthetic peptide fragment derived from the vasopressin hormone sequence, specifically designed for advanced biochemical research and development. This compound is critical for studying receptor-ligand interactions, signal transduction pathways, and the structural biology of neurohypophyseal hormones. It serves as a high-purity reference standard and key intermediate for pharmaceutical R&D teams, academic institutions, and biotechnology companies focused on endocrinology, neuroscience, and peptide-based therapeutic discovery.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and assay validation in drug development pipelines.
• Biochemical Research: Essential for in vitro studies investigating the structure-activity relationship (SAR) of vasopressin and its analogs.
• Receptor Binding Assays: Employed in competitive binding studies to characterize and quantify vasopressin receptor (V1a, V1b, V2) affinity and selectivity.
• Peptide Synthesis Intermediate: Serves as a key building block for the solid-phase or solution-phase synthesis of longer, modified vasopressin-related peptides.
• Academic & Clinical Research: Supports fundamental research into water balance, blood pressure regulation, and social behavior mechanisms.
• Diagnostic Development: Potential use in the development of immunoassays or diagnostic kits targeting vasopressin pathways.

Basic Information

Product Name	(Pyr4, Cys-Cys6, Arg8)-Vasopressin*Fragment 4-8
CAS No.	87558-80-3
Molecular Formula	C30H49N13O8S2
Molecular Weight	759.92 g/mol
Synonyms	[Arg8]-Vasopressin (4-8); AVP (4-8); Vasopressin fragment 4-8; Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (cyclic 1-6 disulfide); Pyr4, Cys-Cys6, Arg8-Vasopressin*Fragment 4-8; Cyclo(1-6)[Cys1,Cys6]-[Pyr4,Arg8]vasopressin(4-8); H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: 1-6)
EINECS	Contact for details

Quality Control

Every batch of (Pyr4, Cys-Cys6, Arg8)-Vasopressin*Fragment 4-8 is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (typically ≥95% by HPLC), and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Amino Acid Composition	Passes test
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.