Description

Fmoc-Ala-Ala-Oh CAS NO 87512-31-0 is a protected dipeptide building block featuring an N-terminal 9-fluorenylmethoxycarbonyl (Fmoc) group. This compound is essential for solid-phase peptide synthesis (SPPS), providing a crucial intermediate for constructing longer, complex peptide sequences with high precision. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in peptide-based drug discovery, therapeutic agent development, and biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the sequential assembly of custom peptides using Fmoc-chemistry protocols.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of novel peptide therapeutics, including hormone analogs and enzyme inhibitors.
• Bioconjugation & Probe Development: Serves as a starting material for creating labeled peptides or peptide-protein conjugates for diagnostic and imaging applications.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Academic & Biochemical Research: Utilized to study peptide structure-activity relationships, protein folding, and enzyme-substrate interactions.
• Process Development & Scale-Up: Acts as a key intermediate in the pilot-scale and commercial-scale manufacturing of peptide active pharmaceutical ingredients (APIs).

Basic Information

Item	Detail
Product Name	Fmoc-Ala-Ala-Oh
CAS No.	87512-31-0
Molecular Formula	C22H24N2O5
Molecular Weight	396.44 g/mol
Synonyms	Fmoc-Ala-Ala-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-alanine; Fmoc-L-alanyl-L-alanine; Fmoc-Ala-Ala; Fmoc-A-A-OH; (2S)-2-[[(2S)-2-[(9H-fluoren-9-ylmethoxy)formamido]propanoyl]amino]propanoic acid; N-Fmoc-L-alanyl-L-alanine; Fmoc-Ala-Ala-COOH
EINECS	Contact for details

Quality Control

Our Fmoc-Ala-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by NMR and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.