Description

Cyclopropanecarboxylic Acid, 1-Amino-2-(3,4-Dihydroxyphenyl)-, trans- (9Ci) is a specialized chiral compound featuring a cyclopropane ring fused to a catechol-bearing amino acid structure. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for organic synthesis. It is primarily utilized by research institutions and pharmaceutical R&D departments for the development of novel active pharmaceutical ingredients (APIs), particularly in neurological and cardiovascular therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates targeting neurological pathways.
• Biochemical Research: Used as a precursor or reference standard in studies involving catecholamine analogs and enzyme inhibition.
• Organic Synthesis Building Block: Employed in asymmetric synthesis to construct complex molecules with cyclopropane and catechol motifs.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Ligand Synthesis: Potential use in the preparation of chiral ligands for catalysis or metal-chelating agents.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-(3,4-Dihydroxyphenyl)-, trans- (9Ci)
CAS No.	87483-05-4
Molecular Formula	C10H11NO4
Molecular Weight	209.20 g/mol
Synonyms	trans-1-Amino-2-(3,4-dihydroxyphenyl)cyclopropanecarboxylic Acid; (1R,2S)-1-Amino-2-(3,4-dihydroxyphenyl)cyclopropanecarboxylic Acid; (1S,2R)-1-Amino-2-(3,4-dihydroxyphenyl)cyclopropanecarboxylic Acid; Catechol Cyclopropane Amino Acid; 2-(3,4-Dihydroxyphenyl)-1-aminocyclopropanecarboxylic Acid; Agaritine analog intermediate; NSC 339313
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, the product should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.